<p id="pg3hu"><tbody id="pg3hu"><var id="pg3hu"></var></tbody></p>

<p id="pg3hu"><strong id="pg3hu"></strong></p>
  • <track id="pg3hu"><ruby id="pg3hu"></ruby></track>
  • <pre id="pg3hu"><label id="pg3hu"></label></pre><object id="pg3hu"><meter id="pg3hu"><address id="pg3hu"></address></meter></object>
      <big id="pg3hu"></big>
      <acronym id="pg3hu"><strong id="pg3hu"></strong></acronym>
    1. <object id="pg3hu"></object>
      <p id="pg3hu"><strong id="pg3hu"><small id="pg3hu"></small></strong></p>

    2. ×

      全国免费热线:400-999-2100

      您身边的细胞培养专家!

      所有分类
      • 所有分类
      • 细胞系
      • 原代细胞
      • 血清
      • 细胞培养基
      • 辅助试剂
      • 细胞凋亡检测试剂盒
      • 细胞房除菌产品
      热搜: 胎牛血清 VERO RAW264.7 成纤维细胞 间充质干细胞 上皮细胞

      忘记密码

      个人邮箱:
      验证码: captcha

      账号激活

      个人邮箱:
      ×
      当前位置:首页 >> 产品中心 >> 细胞资源库 >> 细胞系 >> 小鼠

      产品中心Cell Resources

      联系我们CONTACT US

      • BV2 (小鼠小胶质细胞) (种属鉴定正确)
      • BV2 (小鼠小胶质细胞) (种属鉴定正确)
      • BV2 (小鼠小胶质细胞) (种属鉴定正确)
      • BV2 (小鼠小胶质细胞) (种属鉴定正确)
      • BV2 (小鼠小胶质细胞) (种属鉴定正确)
      • BV2 (小鼠小胶质细胞) (种属鉴定正确)
      • BV2 (小鼠小胶质细胞) (种属鉴定正确)

      BV2 (小鼠小胶质细胞) (种属鉴定正确)

      货号:CL-0493

      规格:1×10?cells/T25培养瓶

      价格: ¥1600

      生长培养基:MEM(含NEAA)10% FBS1% P/S

      数量: - +

      • BV2 (小鼠小胶质细胞) (种属鉴定正确)
      • BV2 (小鼠小胶质细胞) (种属鉴定正确)
      • BV2 (小鼠小胶质细胞) (种属鉴定正确)
      • BV2 (小鼠小胶质细胞) (种属鉴定正确)
      • BV2 (小鼠小胶质细胞) (种属鉴定正确)
      • BV2 (小鼠小胶质细胞) (种属鉴定正确)
      • BV2 (小鼠小胶质细胞) (种属鉴定正确)

      推荐搭配

      套餐一:

      BV2 (小鼠小胶质细胞) (种属鉴定正确) ¥1600
      BV2细胞专用培养基
      • ¥350
      • ¥450

      现单独购买该产品也可享受限时优惠价!

      细胞培养最优解!

      套餐组合价:¥1950¥2050

      加入购物车

      搭配套餐已成功加入购物车!

      产品概述
      产品信息
      名称 BV2 (小鼠小胶质细胞) (种属鉴定正确)
      别称 BV-2
      背景描述 BV-2细胞是由E·Blasi建立于1990年;BV-2细胞由小鼠小神经胶质细胞经逆转录病毒介导转染v-raf/v-myc获永生化。BV-2细胞保留有小神经胶质细胞多种形态、表征和功能特征;免疫组化结果显示,BV-2细胞为MAC1、MAC2阳性;而MAC3、胶质细胞原纤维酸性蛋白、半乳糖脑苷脂为阴性。
      组织来源 脑;胶质瘤
      生长特性 半贴半悬
      细胞形态 上皮细胞样
      细胞类型 转化细胞系
      生长培养基 MEM(含NEAA)10% FBS1% P/S
      推荐传代比例 1:2-1:4
      推荐换液频率 2~3次/周
      冻存条件 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮
      培养条件 气相:空气,95%;CO2,5% 温度:37℃
      STR鉴定
      • STR位点信息
        18-3 16,17
        6-7 15
        5-5 17
        X-1 27
        1-2 19
        7-1 26.2
        8-1 16
        1-1 16,17
        19-2 13
        15-3 22.3,23.3,24.3
        12-1 17
        6-4 18
        4-2 20.3
        3-2 14
        2-1 16
        13-1 17.1
        11-2 16
        17-2 15
      • STR鉴定图
      参考文献
      文献列表
      • NLRP12 collaborates with NLRP3 and NLRC4 to promote pyroptosis inducing ganglion cell death of acute glaucoma(2020/04/15)

        作者:Hui Chen, Yang Deng, Xiaoliang Gan

        期刊:Molecular Neurodegeneration

        DOI:10.1186/s13024-020-00372-w

        影响因子 :18.879

        引用产品:CL-0493

      • ROS-responsive 18β-glycyrrhetic acid-conjugated polymeric nanoparticles mediate neuroprotection in ischemic stroke through HMGB1 inhibition and microglia polarization regulation(2022/04/01)

        作者:Lulu Jin, Zhixin Zhu, Liangjie Hong

        期刊:Bioactive Materials

        DOI:10.1016/j.bioactmat.2022.03.040

        影响因子 :16.8740

        引用产品:CL-0493

      • Tracking autophagy process with a through bond energy transfer-based ratiometric two-photon viscosity probe(2022/06/15)

        作者:Shuyang Zhai, Wei Hu, Weibo Wang

        期刊:BIOSENSORS & BIOELECTRONICS

        DOI:10.1016/j.bios.2022.114484

        影响因子 :12.5450

        引用产品:CL-0493

      • Immunomodulation of MiRNA-223-based nanoplatform for targeted therapy in retinopathy of prematurity(2022/09/12)

        作者:Keke Huang, Zhiqing Lin, Yuanyuan Ge

        期刊:JOURNAL OF CONTROLLED RELEASE

        DOI:10.1016/j.jconrel.2022.08.006

        影响因子 :11.4670

        引用产品:CL-0190 CL-0493 PM150411

      • Olfactory bulb microglia activation mediated neuronal death in real-ambient particulate matter exposure mice with depression-like behaviors(2022/01/29)

        作者:Xiaoya Ji, Rui Liu, Jiajun Guo

        期刊:Science Of The Total Environment

        DOI:10.1016/j.scitotenv.2022.153456

        影响因子 :10.7530

        引用产品:CL-0168 CL-0493

      • Decellularized extracellular matrix and mesenchymal stem cells promote recovery in traumatic brain injury by synergistically enhancing neurogenesis and attenuating neuroinflammation(2022/10/01)

        作者:Xuewei Zhang, Bixue Wang, Hua Hong

        期刊:JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY

        DOI:10.1016/j.jmst.2022.08.028

        影响因子 :10.3190

        引用产品:CL-0493 CP-M131

      • Immune-responsive gene 1/itaconate activates nuclear factor erythroid 2-related factor 2 in microglia to protect against spinal cord injury in mice(2022/02/10)

        作者:Libin Ni, Jian Xiao, Di Zhang

        期刊:Cell Death & Disease

        DOI:10.1038/s41419-022-04592-4

        影响因子 :9.685

        引用产品:CL-0412 CL-0493

      • Erbin protects against sepsis-associated encephalopathy by attenuating microglia pyroptosis via IRE1α/Xbp1s-Ca2+ axis(2022/09/28)

        作者:Guoqing Jing, Jing Zuo, Qing Fang

        期刊:Journal of Neuroinflammation

        DOI:10.1186/s12974-022-02598-5

        影响因子 :9.5870

        引用产品:CL-0493 CL-0697

      • Gold nanocluster & indocyanine green based triple-effective therapy for MRSA infected central nervous system(2022/04/04)

        作者:Yi Zhuo, Yi Zhang, Bing Wang

        期刊:Applied Materials Today

        DOI:10.1016/j.apmt.2022.101453

        影响因子 :8.6630

        引用产品:CL-0122 CL-0137 CL-0493 CL-0598

      • Study on the antidepressant effect of panaxynol through the IκB-α/NF-κB signaling pathway to inhibit the excessive activation of BV-2 microglia(2021/03/13)

        作者:Yan Zhao, Xialin Sun, Tingwen Zhang

        期刊:Biomedicine & Pharmacotherapy

        DOI:10.1016/j.biopha.2021.111387

        影响因子 :7.419

        引用产品:CL-0493 PM150210

      • Design and synthesis of 3-(4-pyridyl)-5-(4-sulfamido-phenyl)-1,2,4-oxadiazole derivatives as novel GSK-3β inhibitors and evaluation of their potential as multifunctional anti-Alzheimer agents(2020/09/28)

        作者:Min Wang, Tongtong Liu, Shiming Chen

        期刊:European Journal Of Medicinal Chemistry

        DOI:10.1016/j.ejmech.2020.112874

        影响因子 :7.088

        引用产品:CL-0493

      • Neuropeptide Y in the amygdala contributes to neuropathic pain-like behaviors in rats via the neuropeptide Y receptor type 2/mitogen-activated protein kinase axis(2022/03/21)

        作者:Wenhui Yan, Wuchao Liu, Junlu Wu

        期刊:Bioengineered

        DOI:10.1080/21655979.2022.2051783

        影响因子 :6.8320

        引用产品:CL-0047 CL-0493

      • Rosmarinic acid attenuates inflammatory responses through inhibiting HMGB1/TLR4/NF-κB signaling pathway in a mouse model of Parkinsons disease(2019/3/4)

        作者:Runxiao Lv, Lili Du, Xueyong Liu

        期刊:Life Sci

        DOI:10.1016/j.lfs.2019.03.030

        影响因子 :6.7800

        引用产品:CL-0493

      • The protective effect of 5-O-methylvisammioside on LPS-induced depression in mice by inhibiting the over activation of BV-2 microglia through Nf-κB/IκB-α pathway(2020/09/19)

        作者:Xialin Sun, Tingwen Zhang, Yan Zhao

        期刊:Phytomedicine

        DOI:10.1016/j.phymed.2020.153348

        影响因子 :6.656

        引用产品:CL-0493

      • Aurantiamide promotes M2 polarization of microglial cells to improve the cognitive ability of mice with Alzheimers disease(2022/09/05)

        作者:Heping Shen, Zhongmei He, Hongyan Pei

        期刊:PHYTOTHERAPY RESEARCH

        DOI:10.1002/ptr.7597

        影响因子 :6.3880

        引用产品:CL-0493

      • Asiatic Acid Attenuates Inflammation Induced by Salmonella via Upregulating LncRNA TVX1 in Microglia(2022/09/19)

        作者:Wenshu Zou, Jingyan Zhang, Kai Zhang

        期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

        DOI:10.3390/ijms231810978

        影响因子 :6.2080

        引用产品:CL-0493

      • Serum Extracellular Vesicle–Derived miR-124-3p as a Diagnostic and Predictive Marker for Early-Stage Acute Ischemic Stroke(2021/07/01)

        作者:Zheng Qi, Yingying Zhao, Yu Su

        期刊:Frontiers in Molecular Biosciences

        DOI:10.3389/fmolb.2021.685088

        影响因子 :6.113

        引用产品:CL-0493

      • The Regulatory NOD-Like Receptor NLRC5 Promotes Ganglion Cell Death in Ischemic Retinopathy by Inducing Microglial Pyroptosis(2021/05/20)

        作者:Yang Deng, Yunzhao Fu, Longxiang Sheng

        期刊:Frontiers in Cell and Developmental Biology

        DOI:10.3389/fcell.2021.669696

        影响因子 :6.081

        引用产品:CL-0493

      • DOK3 is involved in microglial cell activation in neuropathic pain by interacting with GPR84(2020/12/03)

        作者:Wenshuang Gao, Yujuan Qu, Juan Huai

        期刊:Aging-US

        DOI:10.18632/aging.202144

        影响因子 :5.9550

        引用产品:CL-0493

      • Rosmarinic acid attenuates inflammatory responses through inhibiting HMGB1/TLR4/NF-κB signaling pathway in a mouse model of Parkinsons disease(2019/03/14)

        作者:Runxiao Lv, Lili Du, Xueyong Liu

        期刊:Life Sciences

        DOI:10.1016/j.lfs.2019.03.030

        影响因子 :5.738

        引用产品:CL-0493

      • High-density lipoprotein reduces microglia activation and protects against experimental autoimmune encephalomyelitis in mice(2022/01/29)

        作者:Shan Hong, Min Niu, Dongmei Meng

        期刊:International Immunopharmacology

        DOI:10.1016/j.intimp.2022.108566

        影响因子 :5.7140

        引用产品:CL-0493

      • Mafenide derivatives inhibit neuroinflammation in Alzheimers disease by regulating pyroptosis(2021/10/10)

        作者:Chenyang Han, Qiaohong Hu, Anqi Yu

        期刊:Journal Of Cellular And Molecular Medicine

        DOI:10.1111/jcmm.16984

        影响因子 :5.295

        引用产品:CL-0493

      • Stress-induced phosphoprotein 1 restrains spinal cord ischaemia-reperfusion injury by modulating NF-κB signalling(2021/11/3)

        作者:Hongdou Jin, Xin Ge, Zhirong Huan

        期刊:Journal Of Cellular And Molecular Medicine

        DOI:10.1111/jcmm.17030

        影响因子 :5.2950

        引用产品:CL-0493

      • Activation of TREM2 attenuates neuroinflammation via PI3K/Akt signaling pathway to improve postoperative cognitive dysfunction in mice(2022/08/27)

        作者:Xue Han, Xiaolei Cheng, Jiyan Xu

        期刊:NEUROPHARMACOLOGY

        DOI:10.1016/j.neuropharm.2022.109231

        影响因子 :5.2730

        引用产品:CL-0493 CL-0697

      • Investigation on the mechanism of mafenide in inhibiting pyroptosis and the release of inflammatory factors(2020/04/30)

        作者:Chenyang Han, Yi Yang, Anqi Yu

        期刊:European Journal of Pharmaceutical Sciences

        DOI:10.1016/j.ejps.2020.105303

        影响因子 :5.112

        引用产品:CL-0493

      • Investigation on the mechanism of mafenide in inhibiting pyroptosis and the release of inflammatory factors(2020/03/12)

        作者:Chenyang Han, Yi Yang, Anqi Yu

        期刊:European Journal Of Pharmaceutical Sciences

        DOI:10.1016/j.ejps.2020.105303

        影响因子 :5.112

        引用产品:CL-0493 CP-M141

      • Covalent Organic Framework (COF): A Drug and Carrier to Attenuate Retinal Ganglion Cells Death in an Acute Glaucoma Mouse Model(2022/08/10)

        作者:Ke Yao, Xin Liang, Guiyang Zhang

        期刊:Polymers

        DOI:10.3390/polym14163265

        影响因子 :4.9670

        引用产品:CL-0493

      • Isolation of Phenolic Compounds from Raspberry Based on Molecular Imprinting Techniques and Investigation of Their Anti-Alzheimer’s Disease Properties(2022/10/14)

        作者:Qian Wu, Abid Naeem, Jiamei Zou

        期刊:MOLECULES

        DOI:10.3390/molecules27206893

        影响因子 :4.9270

        引用产品:164210 164210-50 CL-0493

      • Long Noncoding RNA SNHG14 Promotes Ischemic Brain Injury via Regulating miR-199b/AQP4 Axis(2021/2/20)

        作者:Guanglin Zhang, Tianxiao Li, Xiaozan Chang

        期刊:Neurochemical Research

        DOI:10.1007/s11064-021-03265-6.

        影响因子 :4.4140

        引用产品:CL-0493

      • Small Extracellular Vesicles of M1-BV2 Microglia Induce Neuronal PC12 Cells Apoptosis via the Competing Endogenous Mechanism of CircRNAs(2022/09/08)

        作者:Sheng Gao, Luyue Bai, Shu Jia

        期刊:Genes

        DOI:10.3390/genes13091603

        影响因子 :4.1410

        引用产品:CL-0493

      • Dihydromyricetin attenuates neuropathic pain via enhancing the transition from M1 to M2 phenotype polarization by potentially elevating ALDH2 activity in vitro and vivo(2020/9/11)

        作者:Wei Zhang, Lingxiao Yang, Longyun Li

        期刊:Annals of Translational Medicine

        DOI:10.21037/atm-20-5838

        影响因子 :3.9320

        引用产品:CL-0493

      • Chuanzhitongluo regulates microglia polarization and inflammatory response in acute ischemic stroke(2022/09/21)

        作者:Qingqing Wang, Bin Han, Xu Man

        期刊:BRAIN RESEARCH BULLETIN

        DOI:10.1016/j.brainresbull.2022.09.015

        影响因子 :3.7150

        引用产品:CL-0493

      • SOCS-1 suppresses neuroinflammation in intracranial hemorrhage by downregulating the c-Fos/KLF4/IL-17A axis(2022/01/30)

        作者:Xiaoliu Dong, Xiuqing Zhang, Shijun Xu

        期刊:EUROPEAN JOURNAL OF NEUROSCIENCE

        DOI:10.1111/ejn.15615

        影响因子 :3.6980

        引用产品:CL-0493

      • Comprehensive analysis of the differential expression profile of microRNAs in rats with spinal cord injury treated by electroacupuncture(2020/5/20)

        作者:Zhidong Zhou, Hejian Li, Hongchun Li

        期刊:Molecular Medicine Reports

        DOI:10.3892/mmr.2020.11161

        影响因子 :3.4230

        引用产品:CL-0493

      • MiR-145 enriched exosomes derived from bone marrow-derived mesenchymal stem cells protects against cerebral ischemia-reperfusion injury through downregulation of FOXO1(2022/09/27)

        作者:Hai Zhou, Jing Zhou, Hongwei Teng

        期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

        DOI:10.1016/j.bbrc.2022.09.089

        影响因子 :3.3220

        引用产品:CL-0493 CM-0493 CP-M131

      • Lidocaine relieves spinal cord ischemia-reperfusion injury via long non-coding RNA MIAT-mediated Notch1 downregulation(2022/01/03)

        作者:Junkai Hou, Huixin Li, Changjiang Xue

        期刊:Journal of Biochemistry

        DOI:10.1093/jb/mvab150

        影响因子 :3.2410

        引用产品:CL-0493

      • Downregulation of MMP1 functions in preventing perineural invasion of pancreatic cancer through blocking the NT-3/TrkC signaling pathway(2022/09/30)

        作者:Xiaoqing Xu, Xiaomin Lu, Liping Chen

        期刊:JOURNAL OF CLINICAL LABORATORY ANALYSIS

        DOI:10.1002/jcla.24719

        影响因子 :3.1240

        引用产品:CL-0493

      • Sesamin suppresses high glucose-induced microglial inflammation in the retina in vitro and in vivo(2022/01/12)

        作者:Jie Zhang, Linlin Li, Fangwei Xiu

        期刊:Journal of Neurophysiology

        DOI:10.1152/jn.00466.2021

        影响因子 :2.9740

        引用产品:CL-0493

      • A Causal Relationship in Spinal Cord Injury Rat Model Between Microglia Activation and EGFR/MAPK Detected by Overexpression of MicroRNA-325-3p(2019/3/25)

        作者:Penghui Yan, Xuejian Wu, Xiaokang Liu

        期刊:J Mol Neurosci

        DOI:10.1007/s12031-019-01297-w

        影响因子 :2.8660

        引用产品:CL-0493

      • A Causal Relationship in Spinal Cord Injury Rat Model Between Microglia Activation and EGFR/MAPK Detected by Overexpression of MicroRNA-325-3p(2019/03/25)

        作者:Penghui Yan, Xuejian Wu, Xiaokang Liu

        期刊:Journal of Molecular Neuroscience

        DOI:10.1007/s12031-019-01297-w

        影响因子 :2.866

        引用产品:CL-0493

      • LncRNA H19 Regulates Lipopolysaccharide (LPS)-Induced Apoptosis and Inflammation of BV2 Microglia Cells Through Targeting miR-325-3p/NEUROD4 Axis(2020/11/17)

        作者:Enyi Gu, Weikun Pan, Kangyao Chen

        期刊:Journal of Molecular Neuroscience

        DOI:10.1007/s12031-020-01751-0

        影响因子 :2.8660

        引用产品:CL-0493 CM-0493

      • Apelin-13 attenuates early brain injury through inhibiting inflammation and apoptosis in rats after experimental subarachnoid hemorrhage(2022/01/09)

        作者:Xiaoyan Shen,?Guiqiang Yuan,?Bing Li?

        期刊:Molecular Biology Reports

        DOI:10.1007/s11033-021-07028-y

        影响因子 :2.7420

        引用产品:CL-0493 CM-R105 CP-R105 PM150410

      • miR‐29c‐3p inhibits microglial NLRP3 inflammasome activation by targeting NFAT5 in Parkinsons disease(2020/03/30)

        作者:Ruili?Wang, Qing?Li, Ya?He

        期刊:Genes To Cells

        DOI:10.1111/gtc.12764

        影响因子 :2.3000

        引用产品:CL-0493

      • Salvianic Acid A Sodium Promotes the Recovery of Motor Function After Spinal Cord Injury in Rats by Reducing Microglia Inflammation through Regulating MIP2/Vdac1/Ndufa12 Signaling Axis(2020/10/20)

        作者:Liping Li, Yuanyuan Liu, Xia Zhao

        期刊:ORTHOPAEDIC SURGERY

        DOI:10.1111/os.12808

        影响因子 :2.2790

        引用产品:CL-0493

      • Long noncoding RNA XIST knockdown relieves the injury of microglia cells after spinal cord injury by sponging miR-219-5p(2021/8/3)

        作者:Xueren Zhong, Yongzheng Bao, Qiang Wu

        期刊:Open Medicine

        DOI:10.1515/med-2021-0292

        影响因子 :2.1230

        引用产品:CL-0493

      • C19-Diterpenoid alkaloids from Aconitum richardsonianum(2022/08/27)

        作者:Feng Xing, Jiang Xie, Yanyan Luo

        期刊:Phytochemistry Letters

        DOI:10.1016/j.phytol.2022.08.003

        影响因子 :1.8730

        引用产品:CL-0493

      • 点击展开收起列表
      朱莎莉

      朱莎莉

      【 湖北、河南 】

      刘本佳

      刘本佳

      【 江苏、上海、安徽 】

      章臣雄

      章臣雄

      【 广东、云南 】

      閤春喜

      閤春喜

      【 四川、陕西、甘肃、西藏 】

      张经理

      张经理

      【 重庆 】

      石文平

      石文平

      【 北京、黑龙江、吉林、辽宁 】

      任施博

      任施博

      【 江西、福建、新疆、海南 】

      李荣枫

      李荣枫

      【 天津、河北、内蒙古、山西 】

      陈雨兰

      陈雨兰

      【 湖南、山东、宁夏、青海 】

      尹国文

      尹国文

      【浙江、广西、贵州】

      06普诺赛技术支持-王丹慧

      06普诺赛技术支持-王丹慧

      【 江苏、安徽 】

      07普诺赛技术支持-徐婷

      07普诺赛技术支持-徐婷

      【 北京 】

      08普诺赛技术支持-赵家麒

      08普诺赛技术支持-赵家麒

      【 湖南、天津、河北、山西、内蒙古 】

      09普诺赛技术支持-黄玲

      09普诺赛技术支持-黄玲

      【 四川、陕西、甘肃、重庆、西藏、浙江 】

      02普诺赛技术支持-张洁

      02普诺赛技术支持-张洁

      【 湖北、江西、新疆、海南 】

      03普诺赛技术支持-林梦君

      03普诺赛技术支持-林梦君

      【 上海、宁夏、青海、山东、福建 】

      04普诺赛技术支持-李欢欢

      04普诺赛技术支持-李欢欢

      【 广东 、广西、贵州、云南 】

      05普诺赛技术支持-黄鹂

      05普诺赛技术支持-黄鹂

      【 辽宁、黑龙江、吉林、河南 】

      微信扫一扫咨询

      在线客服
      关闭
      在线咨询
      联系销售
      技术支持

      关注微信公众号

      h片在线播放资源站
      <p id="pg3hu"><tbody id="pg3hu"><var id="pg3hu"></var></tbody></p>

      <p id="pg3hu"><strong id="pg3hu"></strong></p>
    3. <track id="pg3hu"><ruby id="pg3hu"></ruby></track>
    4. <pre id="pg3hu"><label id="pg3hu"></label></pre><object id="pg3hu"><meter id="pg3hu"><address id="pg3hu"></address></meter></object>
        <big id="pg3hu"></big>
        <acronym id="pg3hu"><strong id="pg3hu"></strong></acronym>
      1. <object id="pg3hu"></object>
        <p id="pg3hu"><strong id="pg3hu"><small id="pg3hu"></small></strong></p>